composition for inducing differentiation of multi-potent neural stem cell into dopaminergic meurons and method for inducing differentiation using the same

摘要

The present invention relates to a composition for inducing differentiation from neurons into dopamine neurons comprising a compound represented by the formula (1), which is a MEK1 / 2 inhibitor (also referred to as 'AS703026'), and a method for differentiation using the same. Dopaminergic neurons differentiated from neural stem cells can be used for cell replacement therapy and gene therapy therapy to treat neurodegenerative diseases such as Parkinson's disease, have.