Antimicrobial peptides with high synergistic effect with antibiotics against multidrug resistant gram-negative bacteria and their uses

摘要

The present invention relates to an antimicrobial peptide having antimicrobial activity against Gram negative multidrug resistant bacteria. More particularly, the present invention relates to an antimicrobial peptide having antimicrobial activity against Gram negative multidrug resistant bacteria, A food additive, a feed additive, a composition for an antimicrobial, and a composition for quasi-antimicrobial use. The antibiotic peptide of the present invention not only exhibits significant antimicrobial activity against Gram-negative bacteria but also exhibits a strong antimicrobial activity only against Gram-positive bacteria and an antibiotic which does not have antimicrobial activity against gram-negative bacteria or has a low antimicrobial activity and the antibiotic peptide of the present invention , It is possible to exhibit an excellent antimicrobial effect against gram-negative bacteria and their antibiotic-resistant bacteria as well as Gram-positive bacteria.