Method and device for sample collection in HPLC columns and transfer of the samples into an MS / LC-MS analysis system for the determination and quantification of analytes, as typically required for the determination of drug levels or biomarkers.

摘要

The invention relates to an HPLC column (15) with a sample receiving part as the actual sample carrier, which is integrated one or more times in an individually labeled cassette (11), the sample receiving, the sample transport, the sample intermediate storage and integration into the LC-MS system ( 36) with the cassette (11) takes place together, a pressure-controlled stapling system receives the sample carrier with the dried sample and the method for analytical task and assignment of the results via the marking on the cassette.