TREATMENT OF PEDIATRIC GROWTH HORMONE DEFICIENCY WITH HUMAN GROWTH HORMONE ANALOGUE

摘要

To provide a treatment of pediatric growth hormone deficiency with human growth hormone analogue.SOLUTION: According to the present invention, a pediatric growth hormone deficiency (PGHD) therapy for a pediatric subject is provided. The therapy comprises administering to a pediatric patient with PGHD a human growth hormone-XTEN (hGH-XTEN) fusion protein in therapeutically effective doses every week, every two weeks, semimonthly, every three weeks, or monthly. This therapy is not inferior compared to the height velocity achieved with daily injections of hGH not linked to XTEN over the same period. In another embodiment, the dose is a bolus dose.SELECTED DRAWING: None