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Compounds, compositions and methods for stratification of cancer patients and cancer treatment

机译:用于癌症患者分层和癌症治疗的化合物,组合物和方法

摘要

The invention relates to improved compounds, in particular Patients with cancer are identified using biomarkers (eg, PDE3A, SLFN12 and / or CREB3L1) that correlate with drug sensitivity, resulting in the agents of the invention (eg, Compounds 1-6 disclosed herein) The method is characterized in that the patient population is treated with
机译:本发明涉及改进的化合物,特别是使用与药物敏感性相关的生物标志物(例如PDE3A,SLFN12和/或CREB3L1)鉴定患有癌症的患者,从而得到本发明的药物(例如本文公开的化合物1-6)该方法的特征在于用

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