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Biomarkers and diagnostic methods for detection of highly pathogenic viral hemorrhagic sepsis virus

机译:用于检测高致病性病毒性出血性败血症病毒的生物标志物和诊断方法

摘要

A biomarker composition includes, as an active ingredient, one or at least two polypeptides having 5 to 120 consecutive amino acids that are selected from the group consisting of an amino acid in which serine (S) at the 56th position is substituted with leucine (L), an amino acid in which serine (S) at the 8th position is substituted with asparagines (N), an amino acid in which threonine (T) at the 81st position is substituted with alanine (A), an amino acid in which valine (V) at the 88th position is substituted with alanine (A), an amino acid in which glycine (G) at the 117th position is substituted with asparatic acid (D), and an amino acid in which glutamic acid (E) at the 119th position is substituted with lysine (K), within an amino acid sequence of VHSV represented by SEQ ID NO: 1.
机译:生物标志物组合物包括一种或至少两种具有5至120个连续氨基酸的多肽作为活性成分,所述多肽选自其中第56位的丝氨酸(S)被亮氨酸(L)取代的氨基酸。 ),第8位的丝氨酸(S)被天冬酰胺(N)取代的氨基酸,第81位的苏氨酸(T)被丙氨酸(A)取代的氨基酸,缬氨酸的氨基酸位于第88位的(V)被丙氨酸(A)取代,位于第117位的甘氨酸(G)被天冬氨酸(D)取代的氨基酸,以及位于谷氨酸(E)的氨基酸被在由SEQ ID NO:1表示的VHSV的氨基酸序列内,第119位被赖氨酸(K)取代。

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