Treatment or prevention agent for ischemic disease, glaucoma, optic nerve disease, retinal degenerative disease, angiogenic retinal disease, cancer, neurodegeneration or autoimmune disease, and hypoxia-inducible factor inhibitor

摘要

Novel HIF inhibitor with low cytotoxicity and suitable for ophthalmic treatment, and ischemic disease, glaucoma, optic nerve disease, retinal degenerative disease, retinal degenerative disease, angiogenic retinal disease, cancer, neurodegeneration, or autoimmune disease A therapeutic or prophylactic agent is provided. The present invention is a therapeutic or preventive agent for ischemic disease, glaucoma, optic nerve disease, retinal degenerative disease, retinal degenerative disease, angiogenic retinal disease, cancer, neurodegeneration, or autoimmune disease, and belongs to the genus Hydrangea A treatment or a treatment containing one or more selected from the group consisting of plants, plants belonging to the genus Narcissus, plants belonging to the genus Grape, plants belonging to the genus Brassica, fishes belonging to the genus Brassica, or the like, as an active ingredient It is a preventive agent.