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Two-phase approach to fourier transform ion mobility time-of-flight mass spectrometry
Two-phase approach to fourier transform ion mobility time-of-flight mass spectrometry
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机译:傅里叶变换离子迁移率飞行时间质谱的两阶段方法
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摘要
The methods herein provide for analysis of ion populations. Certain aspects include: obtaining a first data set that includes: a first binary On-OFF frequency sweep across a range of frequencies resulting in a first raw data in the time domain and obtaining a second data set that includes: a second binary On-OFF frequency sweep 180° out of phase from the first binary On-OFF frequency sweep so as to result in a second raw data in the time domain from received ion current resulting from the second binary On-OFF frequency sweep. Thereafter the two data sets are combined to provide for raw mobility signals of the ion populations in the time domain for each m/z over a range of selected m/z values. Additional aspects include a hybrid system for performing the methods disclosed herein.
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