METHODS FOR STABILIZING COLLAGEN-CONTAINING TISSUE PRODUCTS AGAINST ENZYMATIC DEGRADATION

摘要

Methods for producing crosslinked tissue matrices, crosslinked tissue matrices produced by such methods, as well as tissue products comprising such tissue matrices are disclosed. The methods comprise (1) dehydrating a collagen-containing tissue matrix to form a dehydrated collagen-containing tissue matrix; and (2) irradiating the dehydrated collagen-containing tissue matrix such that at least a portion of the dehydrated collagen-containing tissue matrix is crosslinked.