首页> 外国专利> DEGLYCOSYLATED ANTIBODY SPECIFICALLY BINDING TO CLEC14A AND USES THEREOF

DEGLYCOSYLATED ANTIBODY SPECIFICALLY BINDING TO CLEC14A AND USES THEREOF

机译:与CLEC14A特异性结合的去糖基化抗体及其用途

摘要

The present disclosure relates to a deglycosylated antibody binding specifically to C-type lectin domain family 14, member A (clec14a). More particularly, the present disclosure relates to a deglycosylated antibody that comprises a light chain variable region comprising CDR1 having a certain sequence and binds specifically to clec14, and use thereof, for example, a pharmaceutical composition containing the antibody for preventing or treating an angiogenesis-related disease.
机译:本公开涉及与C型凝集素结构域家族14的成员A(clec14a)特异性结合的去糖基化抗体。更具体地,本公开涉及一种去糖基化抗体,其包含轻链可变区,该轻链可变区包含具有一定序列的CDR1并特异性地与clec14结合,及其用途,例如,包含该抗体的药物组合物用于预防或治疗血管生成-相关疾病。

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