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DISEASE AFFECTION DETERMINATION DEVICE, DISEASE AFFECTION DETERMINATION METHOD, AND DISEASE AFFECTION DETERMINATION PROGRAM

机译:疾病影响确定装置,疾病影响确定方法和疾病影响确定程序

摘要

To enable disease affection determination by using a neural network to perform learning using data of the expression levels of biomarkers, and to enable extraction of a feature biomarker for a disease by the neural network. Sample data in which respective expression levels of a plurality of types of biomarkers are recorded for each individual is acquired, a learned model in which affection of diseases is determinable obtained in advance by performing machine learning using training data is generated, a plurality of sample data to which label information of disease affection is attached is input to the learned model and calculation is performed, the degrees of importance of respective feature of a plurality of biomarkers obtained with the learned model are quantified by affection determination calculation, for each sample data, and a predetermined number of biomarkers are extracted as feature biomarkers regarding the disease on the basis of the quantified degrees of importance of all the sample data for each biomarker.
机译:为了通过使用神经网络来进行疾病影响确定,以使用生物标志物的表达水平的数据进行学习,并能够通过神经网络提取疾病的特征生物标志物。获取其中每个个体记录了多种生物标志物的各个表达水平的样本数据,生成了学习模型,其中通过使用训练数据进行机器学习来预先获得可确定疾病的影响的学习模型,多个样本数据将附着有疾病情感的标签信息的信息输入到学习模型并进行计算,对于每个样本数据,通过情感确定计算来量化利用学习模型获得的多个生物标志物各自特征的重要程度,并且基于每个生物标记物的所有样本数据的量化的重要程度,提取预定数量的生物标记物作为关于疾病的特征生物标记物。

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