COMPOSITION ACCORDING TO FORMULA IAV, OR A PHARMACEUTICALLY ACCEPTABLE SALT, SOLVATO, Polymorph, OR PRODUCT OF THE SAME; COMPOUND; 2-MORPHOLINE-N- (3- (4- (5- (PYROLIDINE-1-CARBONYL) -1H-PYROL-3-IL) THIAZOL-2-IL) ACETAMIDE CHLORIDRATE SALT POLYMORPH; ACIDATED INGREDIENT CONSTITUTED WITH THE SAME; PHARMACEUTICAL COMPOSITION; 2-MORPHOLIN-N- (3- (4- (5- (PYROLIDINE-1-CARBONYL) 1H-PYROL-3-IL) TIAZOL-2-IL) PHENYL) ACETAMIDE (POLYMORPH) (I); ACTIVE INGREDIENT CONSTITUTED BY THE SAME; USE OF A PHARMACEUTICALLY ACCEPTABLE COMPOUND OR SALT, SOLVATO, POLYMORPH OR PRODUCT OF THE SAME AND USE OF A POLYMORPH OR ACTIVE INGREDIENT OF 2-MORPHOLIN-N- (3- (4- (5- (PYROLIDINE-1-CARBONIL)) -1H-PYRROL-3-IL CHLORIDE TIAZOL-2IL) TIAZOL-2-IL) PHENYL) ACETAMIDE (FORMULA I) AND USE OF A POLYMORPH OR ACTIVE INGREDIENT OF 2-MORPHOLINO-N- (3- (4- (5- (PYROLIDINE-1-CARBONYL) -1H1PIRROL -3-IL) TIAZOL-2-IL) PHENYL) ACCEPTED (FORMULA I) IN THE MANUFACTURE OF A MEDICINAL PRODUCT

摘要

compound according to formula iav, or a pharmaceutically acceptable salt, solvate, polymorph, or prodrug thereof; compound; 2-morpholin-n- (3- (4- (5- (pyrrolidin-1-carbonyl) -1h-pyrrol-3-yl) thiazol-2-yl) phenyl) acetamide hydrochloride salt polymorph (formula i) ; active ingredient consisting thereof; pharmaceutical composition; 2-morpholin-n- (3- (4- (5- (pyrrolidin-1-carbonyl) -1H-pyrrol-3-yl) thiazol-2-yl) phenyl) acetamide polymorph (formula i); active ingredient consisting thereof; use of a pharmaceutically acceptable compound or salt,solvate, polymorph or prodrug thereof and use of a polymorph or active ingredient of 2-morpholine-n- (3- (4- (5-pyrrolidin-1-carbonyl) -1h-pyrrol-3-yl) thiazol-hydrochloride salt). 2-yl) phenyl) acetamide (formula i) and use of a 2-morpholine-n- (3- (4- (5- (pyrrolidin-1-carbonyl) -1h-pyrrol-3) polymorph or active ingredient il) thiazol-2-yl) phenyl) acetamide (formula i) in the manufacture of a medicament the invention relates to the compounds and methods for modulating components of a kinase signaling cascade.