1- {2- 4- (2-amino-5-chloro-3-pyridinyl) phenoxy -5-pyrimidinyl} -3- 2- (methylsulfonyl) -5- (trifluoromethyl) phenyl urea salt thereof , pharmaceutical composition comprising them and their use for cancer treatment

摘要

1- {2- [4- (2-amino-5-chloro-3-pyridinyl) phenoxy] -5-pyrimidinyl} -3- [2- (methylsulfonyl) -5- (trifluoromethyl) phenyl] urea salt thereof A pharmaceutical composition comprising them and their use for cancer treatment The present invention provides the compound 1- {2- [4- (2-amino-5-chloro-3-pyridinyl) phenoxy] -5-pyrimidinyl} -3 - [2- (methylsulfonyl) -5- (trifluoromethyl) phenyl] urea, a salt of this compound, as well as a pharmaceutical composition comprising both the compound and its salt as an active ingredient. The present invention also relates to or use of this compound and its salt for the manufacture of a prophylactic and / or therapeutic agent for the treatment of cancer, such as prostate cancer, pancreatic cancer, breast cancer, blood cancer, gland cancer. thyroid, cervical cancer, neuroblastoma or lung cancer.