ISOLATED NUCLEIC ACID MOLECULATION, COMPOSITION, AND METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST FILOVIRUS AND EBOLAVIRUS, TREATMENT OF AN INDIVIDUAL WHO HAS BEEN DIAGNOSED WITH EBOLAVIRUS AND PREVENTION OF EBOLAVIRUS INFECTION

摘要

nucleic acid molecules and compositions comprising one or more nucleic acid sequences encoding ebolavirus consensus glycoprotein immunogens are disclosed. coding sequences optionally include an operably linked coding sequence encoding a signal peptide. Immunomodulatory methods and methods of inducing an immune response against ebolaviruses are disclosed. an ebolavirus prevention method and methods of treating ebolavirus infected individuals are disclosed. ebolavirus consensus proteins are disclosed.