molecule, pharmaceutical composition, and in vitro methods for predicting and / or diagnosing and / or assessing the risk of developing and / or monitoring progression and / or monitoring the effectiveness of a therapeutic treatment and / or screening for a therapeutic treatment of a tumor, to treat and / or prevent tumor and to identify a molecule.

摘要

The present invention relates to a molecule capable of modulating the expression and / or function of at least one marker that is selectively dysregulated in the tumor infiltration regulatory t-cell or a molecule capable of specifically binding to at least one marker that is selectively deregulated T-cell regulating tumor infiltration and induce antibody-dependent cell-mediated cytotoxicity (adcc) for use in the prevention and / or treatment of cancer or for use in a method for depleting T-cell regulating tumor infiltration in alive in a subject or for use in a method for enhancing tumor immunity in a subject and relative pharmaceutical composition.