首页> 外国专利> METHODS FOR DETECTION OF AT LEAST A NOROVIRUS GENOGROUP IN A STORAGE SAMPLE AND FOR SELECTING A PATIENT SUFFERING FROM ACUTE GASTROENTERITE, AND, KIT

METHODS FOR DETECTION OF AT LEAST A NOROVIRUS GENOGROUP IN A STORAGE SAMPLE AND FOR SELECTING A PATIENT SUFFERING FROM ACUTE GASTROENTERITE, AND, KIT

机译:检测存储样本中至少一种诺如病毒基因组并从急性胃肠道肠胃炎中选择患者的方法

摘要

The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit norovirus genogroup i (gi) or norovirus genogroup ii (gii). The methods described herein are based on the detection of norovirus genogroup i (gi) and norovirus genogroup ii (gii) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing time reverse transcriptional pcr real. Kits for use in the practice of the methods are also provided.
机译:本公开提供了用于确定表现出急性胃肠炎的患者是否将从抑制诺如病毒基因组i(gi)或诺如病毒基因组ii(gii)的治疗剂的治疗中受益。本文所述的方法基于粪便样品中诺如病毒基因组i(gi)和诺如病毒基因组ii(gii)的检测,而无需在执行时间逆转录pcr real之前从临床样本中提取病毒核酸。还提供了用于实施该方法的试剂盒。

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