clozapine extended release pharmaceutical composition in multiparticulate form and process for the preparation of a clozapine extended release pharmaceutical composition

摘要

The present invention relates to a clozapine prolonged release pharmaceutical composition. The present invention provides a sustained release pharmaceutical composition comprising clozapine, a sealing coating, an acid coating and a sustained release coating. The invention is particularly suited for dispensing once a day a solid oral pharmaceutical formulation which releases a therapeutically effective amount of clozapine over an extended period of time.