a process for obtaining continuous diploid avian cell lines, a virus replication process in a continuous diploid avian cell line, and a recombinant peptide and protein production process

摘要

A process for obtaining continuous diploid avian cell lines, a virus replication process in a continuous diploid avian cell line, and a recombinant peptide and protein production process The present invention relates to the development and manufacture of viral vaccines. in particular the invention relates to the field of industrial production of vaccines and viral vectors, more particularly to the use of avian embryonic stem cells, preferably the duck embryonic stem cell ebx® cell line, to the production of viruses and viral vectors. The invention is particularly useful for the industrial production of viral vaccines for the prevention of human and animal viral infection.