NETHERLANDS, NETHERLANDS, YOURSELF, YOURSELF AND YOURSELF, AS DRIVING DEVICES

摘要

Compounds of the type (I) or stereoisomer,Identical or medically acceptable salts or derivatives thereof,where R1, R2, Ra, Rb, Rc, Rd, X,ring B and ring C are as defined here and where ring B and section NH-C(=X)-NH are in trans-stereochemical formation,are inhibitors of TrkA kinase and are useful in treating diseases that can be treated with a TrkA kinase inhibitor such as pain,cancer,inflammation/inflammatory diseases,neurodegenerative diseases,specific infectious diseases,Sjogren syndrome, endometriosis,diabetic peripheral neuropathy,Protectitis or pelvic pain syndrome.