USE OF THE ANTI-ALPHA-V INTEGRIN ANTIBODY DI17E6 IN THE PRODUCTION OF A MEDICAMENT AND TREATMENT OF PROSTATE CANCER, METHOD OF TREATING CASTRATION-RESISTANT PROSTATE CANCER (CRPC), METHOD OF DECLINING THE PSA LEVEL, METHOD OF REDUCING PAIN OCCURRING IN PROSTATE CANCER

摘要

The invention relates to the use of the anti-αv integrin antibody DI17E6 or a biologically active variant or modification thereof, wherein said variant or modification comprises a constant region which is at least 80-98% identical in amino acid sequence compared to the constant region of DI17E6, for the treatment or production of a medicament for treating patients suffering from castration-resistant prostate cancer and to a corresponding method of the treatment.