3β, 11α-dihydroxyandrost-5-en-7,17-dione and method for producing new 3β, 11α-dihydroxyandrost-5-en-7,17-dione

摘要

the application concerns a method of production 3u00df, 11? - dihydroksyandrost - 5 - en - 7,17 hydrochloride of formula 2. as a result of the action of enzyme contained in cells of strain of beauveria caledonica kch j3.4 of sequence 1, followed by hydroxylation at carbon atom c - 7, the oxidation of hydroxyl groups with the coal group viewed karbonylowej and stereoselektywna hydroxylation by the atom in u0119gla c - 11.thus obtained product is secreted from the aqueous culture of the micro organism, known way, by extraction with an organic solvent niemieszaju0105cym with water (chloroform).