PROCEDURE FOR PREPARATION OF OVOCITS AND / OR MAGNETIC EMBRYOS THROUGH NANOPARTICLES FOR ASSISTED REPRODUCTION TECHNIQUES AND USE IN ASSISTED REPRODUCTION TECHNIQUES OF OVOCITS AND / OR NON-HUMAN EMBRYOS PREPARED WITH SUCH PROCEDURE

摘要

Procedure for preparing oocytes and / or magnetic embryos by means of nanoparticles for assisted reproduction techniques and for use in techniques for assisted reproduction of oocytes and / or non-human embryos prepared with said procedure, said procedure comprising: a stage where magnetic nanoparticles are conjugated with OVGP1r recombinant oviductin protein; a step in which it is verified that the nanoparticles-OVGP1r conjugate binds to the oocyte / embryo ZP after their joint incubation; and a stage in which the number of oocytes / embryos having nanoparticles distributed around the ZP without being endocitated is checked, and it is evaluated whether the amount of the magnetic nanoparticles bound to the ZP of oocytes / embryos is sufficient to be attracted by a magnetic field