THERAPEUTIC COMPOSITIONS INCLUDING MITOCHONDRIAL CELL-PENETRATING PEPTIDES, GLUTATHIONE ANALOG PEPTIDES, AND FUSIONS THEREOF, AND USES OF THE COMPOSITIONS TO TREAT AND PREVENT MITOCHONDRIAL DISEASES AND CONDITIONS

摘要

Disclosed herein are methods and compositions related to the treatment and/oramelioration of diseases and conditions comprising administration ofmitochondrialantioxidative penetrating peptides (MAPPs), or pharmaceutically acceptablesaltsthereof. In particular, the present technology relates to administering aneffectiveamount of a MAPP to a subject in need thereof to prevent or treat a disease ormedicalcondition, reduce risk factors associated with a disease or medical condition,and/orreducing the severity of a medical disease or condition.