首页> 外国专利> APPLICATION OF CEFMINOX IN PREPARATION OF MEDICINE FOR PREVENTING/TREATING PULMONARY HYPERTENSION

APPLICATION OF CEFMINOX IN PREPARATION OF MEDICINE FOR PREVENTING/TREATING PULMONARY HYPERTENSION

机译:头孢米诺在预防/治疗肺动脉高压的药物制备中的应用

摘要

The present invention provides an application of Cefminox in the preparation of a medicine for preventing/treating pulmonary hypertension. Through pharmacological experiments on the preventive and therapeutic effect of Cefminox on PAH in rats induced by monocrotaline, the inventors confirm that the curative effect of Cefminox is good and significantly better than that of existing medicines in a control group. Cefminox can reduce pulmonary artery pressure at lower doses by pulmonary administration, with a curative effect significantly better than that of intravenous administration. The present invention provides a new medicine for preventing/treating pulmonary hypertension and has a bright clinical application prospect.
机译:本发明提供了头孢米诺在制备用于预防/治疗肺动脉高压的药物中的应用。通过对头孢克林诱导的头孢克肟对大鼠多环芳烃的预防和治疗的药理实验,发明人证实了头孢米诺的治疗效果好于对照组,且明显优于对照组。头孢米诺可以通过肺部给药以较低的剂量降低肺动脉压力,其疗效明显优于静脉内给药。本发明提供了一种预防/治疗肺动脉高压的新药,具有广阔的临床应用前景。

著录项

  • 公开/公告号WO2018219188A1

    专利类型

  • 公开/公告日2018-12-06

    原文格式PDF

  • 申请/专利权人 SHANGHAI HOFFEN PHARMACEUTICAL CO. LTD.;

    申请/专利号WO2018CN87993

  • 发明设计人 LIU FUYIN;

    申请日2018-05-23

  • 分类号A61K31/545;A61K31/546;A61P9/12;

  • 国家 WO

  • 入库时间 2022-08-21 11:57:53

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