首页> 外国专利> BACTERIOPHAGE ENGINEERING VIA METHODS INVOLVING GIBSON ASSEMBLY

BACTERIOPHAGE ENGINEERING VIA METHODS INVOLVING GIBSON ASSEMBLY

机译：通过涉及吉布森组件的方法进行噬菌体工程

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摘要

The present disclosure provides methods of generating recombinant bacteriophage genomes via semi-synthesis. Specifically, the present technology provides methods of integrating a heterologous nucleic acid sequence into a bacteriophage genome, and isolating recombinant bacteriophages that express the heterologous nucleic acid sequence.

机译：本公开提供了通过半合成 生成重组噬菌体基因组的方法。具体地，本技术提供了将异源核酸序列整合到噬菌体基因组中，并分离表达异源核酸序列的重组噬菌体的方法。 展开▼

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公开/公告号WO2019032576A3

专利类型

公开/公告日2019-03-21

原文格式PDF

申请/专利权人 THE CHARLES STARK DRAPER LABORATORY INC.;
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申请/专利号WO2018US45597

发明设计人 MCFARLAND KIRSTY A.;ROGERS MILES T.;MCBRINE CONNOR;HOLDER JASON;
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申请日2018-08-07

分类号C12N7/02;C12N15/66;

国家 WO

入库时间 2022-08-21 11:56:39

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4. Next-Gen Shotgun Cloning Using the Gibson Assembly Method [J] . Christine Chen, Steven Thomas, Nate Maynard Genetic Engineering & Biotechnology News: The Information Source of the Biotechnology Industry . 2015,第13期

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