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HIGH-EFFICIENCY, ARRAY-BASED, SINGLE-CELL SEQUENCING PREP SYSTEM THAT CORRELATES CELL PHENOTYPE WITH GENOTYPE
HIGH-EFFICIENCY, ARRAY-BASED, SINGLE-CELL SEQUENCING PREP SYSTEM THAT CORRELATES CELL PHENOTYPE WITH GENOTYPE
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机译:高效,基于阵列的单细胞测序准备系统,可将细胞表型与基因型相关
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摘要
A particle-sorting device includes a housing having an inlet for receiving first and second types of cells, a first outlet through which cells of the first type are expelled from the housing and a second outlet through which cells of the second type are expelled from the housing. The housing further includes an interrogation zone in which cells passing through the interrogation zone are determined by a sensing device to be of the first type or the second type. An electromagnet is in signal communication with a processing device. A shunting device is disposed within the housing, which includes ferromagnetic material and is configured to block flow through the second outlet in response to creation of a magnetic field by the electromagnet. The processing device causes the electromagnet to create the magnetic field in response to the sensing device determining that a cell of the first type has passed through the interrogation zone.
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