SINGLE NUCLEOTIDE POLYMORPHISM LOCI ASSOCIATED WITH MAJOR ADVERSE CARDIOVASCULAR EVENTS AND APPLICATION THEREOF

摘要

Disclosed in the present invention are 17 single nucleotide polymorphism (SNP) loci associated with major adverse cardiovascular events (MACEs) and an application thereof. The 17 SNP loci provided by the present application are obtained on the basis of large-scale follow-up visits and data analysis on patients suffering from coronary heart disease, and may be used as markers for predicting the occurrence of major adverse cardiovascular events. In addition, further comprised by the present application is a kit for predicting the occurrence of MACEs in a subject, which comprises primer pairs and probe pairs used for amplifying and detecting the described 17 SNP loci, being capable of predicting the risk of MACEs in subjects.