- Nanoliposome-microbubble assemblies encapsulating a durg for the treatment of androgenic alopecia and composition comprising the same for improving or treating hair loss

摘要

The present invention relates to a nanoliposome-microbubble conjugate in which a drug for treating hair loss such as finasterid, Minoxidil, and Dutasteride is encapsulated, and a composition for alleviating or treating hair loss containing the same. Oral administration such as finasterid which is currently used as a hair loss treatment body is most preferable to be delivered by scalp application due to various side effects caused by oral administration, but the scalp application alone has the disadvantage that the drug is not well delivered to the hair follicle cells. In addition, various side effects occur in the drug for treating hair loss used as an external preparation for skin, so that the lowering of the use concentration is needed. Therefore, utilizing a delivery support to increase the drug delivery efficiency of finasterid is important. When the nanoliposome-microbubble conjugate of the present invention is used the delivery efficiency of the drug for treating hair loss can be enhanced, which is treated at a low concentration, and thus can effectively treat male pattern hair loss.