miRNA-31-5p The biomarker miRNA-31-5p for diagnosis of pre-eclampsia and use thereof

摘要

The present invention relates to miR-31-5p, a biomarker for the diagnosis of gestosis, and a use thereof. Specifically, the present invention relates to a composition for predicting or diagnosing gestosis a comprising a substance for measuring the concentration of miR-31-5p, a kit comprising the composition, and a method for providing information necessary for prediction or diagnosis of gestosis using miR-31-5p. According to the present invention, miR-31-5p can be used as a biomarker to accurately diagnose or predict gestosis. In particular, the biomarker of the present invention has a significant correlation with sEng and sFlt-1, conventional biomarkers, and has excellent sensitivity and specificity as a biomarker for the diagnosis of gestosis.