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-AMATOXIN-CONJUGATES WITH IMPROVED LINKAGES

机译：-阿托莫辛-缀合物具有改进的键合

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摘要

The present invention is directed to tumor therapy. In one aspect, the invention is directed to a conjugate linked by a specific linkage of an antibody to a target-binding moiety, such as an amoxicine, which is useful for treating cancer. In another aspect, the present invention is directed to a pharmaceutical composition comprising such a conjugate.

机译：本发明涉及肿瘤治疗。一方面，本发明涉及通过抗体与靶标结合部分例如阿莫西辛的特异性连接而连接的缀合物，其可用于治疗癌症。在另一方面，本发明涉及包含这种缀合物的药物组合物。

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公开/公告号KR101988005B1

专利类型
公开/公告日2019-06-11

原文格式PDF
申请/专利权人 하이델베르크 파마 리서치 게엠베하;
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申请/专利号KR20137026713
发明设计人 지몬 베르너;루츠 크리스티안;뮐러 크리스토퍼;안데를 얀;
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申请日2012-03-09
分类号A61K47/48;A61K39/395;A61P35;
国家 KR
入库时间 2022-08-21 11:48:25

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