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ESBL ECO4 Novel ESBL producing Escherichia coli specific bacteriophage ECO4 and antibacterial composition comprising the same

机译:ESBL ECO4新型的产生ESBL的大肠杆菌特异性噬菌体ECO4和包含其的抗菌组合物

摘要

The present invention includes a novel bacteriophage ECO4 having an exterminating ability specific to E. coli, particularly ESBL-producing E. coli, an antibiotic composition containing the bacteriophage, a feed composition, a feed, a disinfectant or a cleansing agent, and a step of administering the bacteriophage to a subject To a method for preventing or treating infectious diseases caused by ESBL-producing E. coli. The method for preventing or treating infectious diseases caused by ESBL producing E. coli using the bacteriophage ECO4 of the present invention is highly specific to pathogenic Escherichia coli as compared with chemicals such as existing antibiotics and the bacteriophage ECO4 is infected with ESBL- And has an advantage of being strong against physicochemical stimulation. In addition, since the bacteriophage ECO4 of the present invention is not infected by any host other than a bacterium such as human, animal, or plant, it can solve problems of antibiotic resistant bacteria caused by misuse of antibiotics, residual antibiotics in food, have. Therefore, the bacteriophage ECO4 of the present invention can be used variously in the fields of prevention or treatment of infectious diseases caused by Escherichia coli, especially ESBL-producing Escherichia coli, antibiotic compositions, composition for feed addition, feed, disinfectant, or detergent.
机译:本发明包括具有特异于大肠杆菌,特别是产生ESBL的大肠杆菌的消灭能力的新型噬菌体ECO4,含有该噬菌体的抗生素组合物,饲料组合物,饲料,消毒剂或清洁剂以及步骤向受试者施用噬菌体的方法预防或治疗由产生ESBL的大肠杆菌引起的感染性疾病的方法。与现有的抗生素等化学药品相比,使用本发明的噬菌体ECO4预防或治疗由产ESBL的大肠杆菌引起的感染性疾病的方法与致病性大肠杆菌具有高度特异性,并且噬菌体ECO4被ESBL-感染。抗物理化学刺激的优势。另外,由于本发明的噬菌体ECO 4除了未被诸如人,动物或植物的细菌感染之外,还没有被任何其他宿主感染,因此它可以解决由于滥用抗生素,食物中残留的抗生素, 。因此,本发明的噬菌体ECO4可以在预防或治疗由大肠杆菌特别是产生ESBL的大肠杆菌引起的传染病,抗生素组合物,饲料添加组合物,饲料,消毒剂或去污剂的领域中多种使用。

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