N-TERMINAL DOMAIN FRAGMENTS, C-TERMINAL DOMAIN FRAGMENTS AND NC FUSION PROTEINS OF EBOLA VIRUS NUCLEOPROTEIN, AND KIT FOR DIAGNOSING EBOLA VIRUS INFECTION USING SAME

摘要

The present invention relates to N-terminal domain fragments, C-terminal domain fragments and NC fusion proteins of the nucleoprotein of Ebola virus, and a kit for diagnosing Ebola virus infection using the same. The N-terminal domain fragment of the Ebola virus nucleoprotein, the C-terminal domain fragment of the Ebola virus nucleoprotein and the NC fusion protein in which the N-terminal domain fragment and the C-terminal domain fragment of the Ebola virus nucleoprotein are combined, according to the present invention, can be mass-produced in Escherichia coli and effectively produce antibodies from various experimental animals. Accordingly, the N-terminal domain fragment of the Ebola virus nucleoprotein, the C-terminal domain fragment of the Ebola virus nucleoprotein, and the NC fusion protein in which the N-terminal domain fragment and the C-terminal domain fragment of the Ebola virus nucleoprotein are combined can be used as an antigen for diagnosing Ebola virus.;COPYRIGHT KIPO 2019