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Biomarker for early diagnosis of hepatocellular carcinoma in precancerous lesion and use thereof

机译:癌前病变肝细胞癌的早期诊断生物标志物及其应用

摘要

The present invention relates to the use of BANF1, PLOD3 and SF3B4 as biomarkers capable of diagnosing and predicting early liver cancer in precancerous lesions. Specifically, the present invention relates to a composition and diagnostic kit for diagnosing early liver cancer comprising one or more markers for diagnosing early liver cancer selected from the group consisting of BANF1, PLOD3, and SF3B4 and a detection agent for the marker. The present invention also relates to a method for detecting one or more early liver cancer diagnostic markers selected from the group consisting of BANF1, PLOD3 and SF3B4 from a patient's sample, and a method for providing information for early liver cancer diagnosis using the marker.
机译:本发明涉及BANF1,PLOD3和SF3B4作为能够诊断和预测癌前病变中的早期肝癌的生物标记物的用途。具体地,本发明涉及用于诊断早期肝癌的组合物和诊断试剂盒,其包含一种或多种用于诊断早期肝癌的标志物,所述标志物选自BANF1,PLOD3和SF3B4以及该标志物的检测剂。本发明还涉及从患者样品中检测选自BANF1,PLOD3和SF3B4的一种或多种早期肝癌诊断标志的方法,以及使用该标志提供用于早期肝癌诊断的信息的方法。

著录项

  • 公开/公告号KR102025005B1

    专利类型

  • 公开/公告日2019-09-24

    原文格式PDF

  • 申请/专利权人 가톨릭대학교 산학협력단;

    申请/专利号KR20180009550

  • 发明设计人 남석우;은정우;신청유;

    申请日2018-01-25

  • 分类号G01N33/68;C12Q1/6886;G01N33/574;

  • 国家 KR

  • 入库时间 2022-08-21 11:47:45

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