5- 5- Recombinant microorganism producing 5-Aminolevulinic acid and method of producing 5-Aminolevulinic acid using the same

摘要

The present invention relates to a recombinant microorganism producing 5-aminolevulinic acid and a method for producing 5-aminolevulinic acid using the same, and more specifically, to controlling the carbon flow by precisely controlling the expression of genes involved in the central carbon flow. The present invention relates to a recombinant microorganism optimized for aminolevulinic acid production and improved productivity of 5-aminolevulinic acid, and a method for producing 5-aminolevulinic acid using the same. When precisely regulating the expression of aceA, a gene involved in the glyoxylate circuit according to the present invention, it is possible to optimize carbon for ALA production without suffering from intracellular metabolic imbalances and to maximize ALA productivity and cell volume. Microorganisms can be produced. In addition, it is possible to produce ALA from glucose with high efficiency using the recombinant microorganism, and thus it can be widely applied in various industries in which ALA is utilized.