U38 U340 U41 A recombinant herpes simplex virus vector comprising the sequences of U38 U340 and U41

摘要

The present invention relates to a vector for producing recombinant herpes simplex virus type 1 (HSV-1) and uses thereof. By using the vector according to one aspect, a portion of the ICP6 gene region of HSV-1 can be deleted and at the same time various foreign genes can be recombined. Thus, HSV-1 manipulation can be facilitated and HSV-1 specific for cancer cells or tumor cells can be produced.