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APPLICATION OF ANTAGONISTS ACTIVATED BY PROTEASE RECEPTORS 1 (PAR-1) FOR PREVENTION AND/OR TREATMENT OF FUNCTIONAL PATHOLOGICAL CONDITION IN PELVIC AND PERINEAL REGIONS
APPLICATION OF ANTAGONISTS ACTIVATED BY PROTEASE RECEPTORS 1 (PAR-1) FOR PREVENTION AND/OR TREATMENT OF FUNCTIONAL PATHOLOGICAL CONDITION IN PELVIC AND PERINEAL REGIONS
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机译:蛋白酶受体1(PAR-1)活化的拮抗剂在预防和/或治疗上腹及会阴区功能性病理疾病中的应用
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摘要
FIELD: medicine.;SUBSTANCE: group of inventions relates to medicine. Use of a PAR1 antagonist selected from vorapaxar, atopaxar, 3-(2-chlorophenyl)-1-[4-(4-fluorobenzyl)piperazin-1-yl]propenone and their pharmaceutically acceptable salts as a drug for the prevention and/or treatment of a functional pathological condition in the pelvic and perineal region, selected from the group irritable bladder syndrome, overactive bladder syndrome, chronic pelvic and perineal pain and urinary incontinence, and a pharmaceutical composition of the same purpose based on these compounds.;EFFECT: technical result consists in reducing the enhanced contractile reactions of the inflamed or overactive bladder.;15 cl, 12 dwg
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