METHOD OF ANALYZING POLYMORPHIC MARKERS IN THE GENES VKORC1, CYP4F2, CYP2C9, CYP2C19, ABCB1, ITGB3 TO DETERMINE INDIVIDUAL SENSITIVITY TO ANTICOAGULANT DRUGS

摘要

FIELD: medicine.;SUBSTANCE: presented group of inventions refers to pharmacogenetics and personalized medicine. Disclosed is a method of analyzing polymorphic markers in genes VKORC1, CYP4F2, CYP2C9, CYP2C19, ABCB1, ITGB3 to determine individual sensitivity to anticoagulant drugs and a set of oligonucleotide probes used in this method.;EFFECT: proposed group of inventions enables analysis in a short time and with low material costs.;4 cl, 2 dwg, 2 tbl, 4 ex