DIAGNOSTIC TECHNIQUE OF PRIMARY-RESISTANT FORM OF SECRETE EXTRACRANIAL GERM CELL TUMOUR IN CHILDREN

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine and represents a diagnostic technique for a primary-resistant form of a secreting extracranial germ cell tumor in children, involving determining an initial value of the alpha-fetoprotein (AFP) level in a patient with a morphologically verified germ cell tumour and AFP level with induction polychemotherapy, characterized by that the second AFP level is determined after two cycles of induction polychemotherapy on 40–43 days of treatment and use is made in Fig. 1 nomograph of the initial AFP level values matching and the AFP level after two cycles of induction polychemotherapy, constructed for a threshold half-elapse time of AFP of 6 days, an initial AFP level is found from the nomograph abscissa, ordinate - its value after two cycles of polychemotherapy, when these values cross the diagonal line of the nomograph, the primary-resistant form of the extracranial germ cell tumour is diagnosed.;EFFECT: method enables diagnosing children with high accuracy, is simple and accessible in use.;1 cl, 4 dwg, 1 ex