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USES OF HUMANIZED COBRA VENOM FACTOR FOR REDUCING OR PREVENTING IMMUNOGENICITY

机译:人工眼镜蛇毒液因子在减少或预防免疫原性中的用途

摘要

The embodiments herein are concerned with methods and hCVF compositions, including pharmaceutical formulations, useful in complement depletion, the reduction or prevention of unwanted immunogenicity or other immune-related reactions, especially as a consequence of administering a biologic therapy. Such methods and compositions have been found to be effective in complement depletion during more than one administration in the same subject, thereby being useful for prolonged/repeated use.
机译:本文的实施方案涉及方法和hCVF组合物,包括药物制剂,其可用于补体耗竭,减少或预防不想要的免疫原性或其他免疫相关反应,特别是由于施用生物疗法而引起的。已经发现,这些方法和组合物在同一受试者的多于一次给药过程中对补体耗竭有效,因此可用于延长/重复使用。

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