METHOD AND DEVICE FOR DETECTING A CARBAPENEMASE-PRODUCING ENTEROBACTERIACEAE

摘要

The present invention is related to a method for the detection of one or several carbapenemases from a Carbapenemase-producing Enterobacteriaceae (CPE) possibly present in a biological sample, the method comprising the steps of providing a support, immobilizing on the support one or several capture reagents interacting with one or several epitope regions of one or several carbapenemases, providing one or several detection reagents interacting with one or several epitope regions of the one or several carbapenemases, the detection reagent or reagents being linked, directly or indirectly, to a label to form one or several detection conjugates, providing a sample to be tested comprising, or not, one or several carbapenemases to detect, bringing the sample into contact with the capture reagent or reagents, revealing a specific binding between one or several carbapenemases present in the sample using the detection reagent or reagents. The invention relates also to an immunochromatographic detection device to implement the method according to the invention.