EXPANDABLE DEVICE FOR CAPTURING REGURGITANT JET, VOLUME, AND FORCE TO EFFECT VENTRICULAR FUNCTION AND REMODELING

摘要

An implant system for capturing a regurgitant jet to effect preserving the atrioventricular pressure gradient and ventricular remodeling in a human heart including an expandable implant for positioning in the atrial/ventricular valve of the human heart and at least partially within the atrium and/or the ventricle, the expandable implant defining a first position for at least partially capturing the atrioventricular pressure gradient and regurgitant trans-valvular blood flow and associated driving forces during systole and a second position for steering flow from the atrium to the ventricle to enhance vorticular flow during diastole; a therapeutic apical base plate attachable to the apex of the heart; and a tethering conduit connected between the expandable implant and the therapeutic apical base plate assembly that transducts the energy and/or forces of captured regurgitant trans-valvular blood flow or atrioventricular pressure to the structures of the ventricle and the ventricular wall.