PROMOTERS DERIVED FROM THE 5' NONTRANSLATED REGION (5'-NTR) OF THE HUMAN CYCLIC NUCLEOTIDE GATED BETA 3 (CNGB3) GENE, EXPRESSION CASSETTES AND VECTORS COMPRISING SAID PROMOTERS, FOR USE TREATING ACHROMATOPSIA AND OTHER DISEASES

摘要

The present invention provides isolated promoters derived from the 5' nontranslated region of the human cyclic nucleotide gated beta 3 (CNGB3) gene, as well as use thereof in transgene expression cassettes, vectors, kits, and methods for treatment of genetic diseases that affect the cone cells of the retina.