Method for producing human psoriasis model mouse and human psoriasis model mouse

摘要

PROBLEM TO BE SOLVED: To establish a model animal capable of analysis in an individual of human psoriasis. The present invention is a human psoriasis model mouse having a mutant CARD14 gene containing a mutation site within the coiled-coil domain of the CARD14 gene. Further, it is preferable that the mutation site is located in a region encoding the C-terminal side of the coiled-coil domain of the CARD14 gene. [Selection diagram] None