GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF α7-NICOTINIC ACETYLCHOLINE RECEPTORS

摘要

To provide novel compounds and pharmaceutical compositions of the same that are suitable as agonists or partial agonists of α7-nicotinic acetylcholine receptors for maintaining, treating and/or improving the cognitive function.SOLUTION: The present invention relates to geminal substituted quinuclidine amide compounds illustrated by the formula (R)-201 in the figure, and pharmaceutical compositions of the same.SELECTED DRAWING: None