Sensitivity analysis method and system for modeling blood flow characteristics

摘要

Embodiments include systems and methods for determining cardiovascular information. A method includes generating an anatomical model of a portion of a patient's vasculature and a computational model of a blood flow characteristic therein; determining a range of uncertainty for an uncertain parameter, clinical variable, and/or geometry of the model; obtaining a probability model comprising statistics for blood flow characteristic calculations, based on the uncertainty value; iteratively modifying the probability model by adjusting the uncertain parameter, clinical variable, and/or geometry using the uncertainty value, to determine statistical variation of the blood flow characteristic with such adjustment; receiving a target confidence level; calculating a blood flow characteristic value and range of variation thereof consistent with the target confidence level, using the computational model and the modified probability model; and outputting the anatomical model, flow characteristic value, and range of variation.