首页> 外国专利> Drug for preventing, treating or preventing metastasis of giant cell tumor that occurs in bone or soft parts, chondrosarcoma, or osteosarcoma, local injection for arterial embolization, and artificial bone

Drug for preventing, treating or preventing metastasis of giant cell tumor that occurs in bone or soft parts, chondrosarcoma, or osteosarcoma, local injection for arterial embolization, and artificial bone

机译:预防,治疗或预防在骨或软组织,软骨肉瘤或骨肉瘤中发生的巨细胞瘤转移的药物,用于动脉栓塞的局部注射和人造骨

摘要

The present invention provides an agent for prophylactic treatment, therapeutic treatment, or prevention of metastasis of giant cell tumor occurring in a bone and soft tissue, chondrosarcoma, or bone sarcoma, a local infusion for artery embolization, and an artificial bone, which comprises a substance having a PPARγ-agonistic activity and/or a PPARγ expression-inducing activity as an active ingredient. The agent for prophylactic treatment, therapeutic treatment, or prevention of metastasis, the local infusion for artery embolization, and the artificial bone of the present invention are a radical therapeutic agent or radical therapeutic material that can cause apoptosis in giant cell tumor occurring in a bone and soft tissue, chondrosarcoma, or bone sarcoma to make the tumor disappear, and can induce differentiation of the tumor into fat cells to make the tumor disappear.
机译:本发明提供了用于预防,治疗或预防在骨和软组织中发生的巨细胞瘤,软骨肉瘤或骨肉瘤的转移,用于动脉栓塞的局部输注剂和人造骨的药剂,其包括具有PPARγ激动活性和/或PPARγ表达诱导活性的物质作为有效成分。本发明的用于预防,治疗或预防转移的试剂,用于动脉栓塞的局部输注剂和人造骨是可以引起骨骼中发生的巨细胞瘤中的细胞凋亡的自由基治疗剂或自由基治疗材料。和软组织,软骨肉瘤或骨肉瘤使肿瘤消失,并能诱导肿瘤分化为脂肪细胞,使肿瘤消失。

著录项

  • 公开/公告号US10653667B2

    专利类型

  • 公开/公告日2020-05-19

    原文格式PDF

  • 申请/专利权人 NIPPON CHEMIPHAR CO. LTD;

    申请/专利号US201415023896

  • 发明设计人 AKIHIKO TAKEUCHI;HIROYUKI TSUCHIYA;

    申请日2014-09-25

  • 分类号A61K31/38;A61K39/395;A61K31/427;C07K16/28;A61K31/425;A61K45/06;A61L31/14;A61L27/54;A61L31/04;A61L31/16;A61K31/4439;G01N33/50;

  • 国家 US

  • 入库时间 2022-08-21 11:31:00

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