首页> 外国专利> Treatment of lipid transport and metabolism gene related diseases by inhibition of natural antisense transcript to a lipid transport and metabolism gene

Treatment of lipid transport and metabolism gene related diseases by inhibition of natural antisense transcript to a lipid transport and metabolism gene

机译:通过抑制天然反义转录物对脂质转运和代谢基因的治疗脂质转运和代谢基因的相关疾病

摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Lipid transport and metabolism gene, in particular, by targeting natural antisense polynucleotides of a Lipid transport and metabolism gene. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of a Lipid transport and metabolism genes.
机译:本发明涉及特别是通过靶向脂质转运和代谢基因的天然反义多核苷酸来调节脂质转运和代谢基因的表达和/或功能的反义寡核苷酸。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与脂质转运和代谢基因表达有关的疾病和病症中的用途。

著录项

  • 公开/公告号US10604755B2

    专利类型

  • 公开/公告日2020-03-31

    原文格式PDF

  • 申请/专利权人 CURNA INC.;

    申请/专利号US201514814895

  • 申请日2015-07-31

  • 分类号C12N15/113;A61K31/7115;A61K31/7125;A61K31/713;A61K48;

  • 国家 US

  • 入库时间 2022-08-21 11:28:37

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