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Anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of Mycobacterium tuberculosis infections

机译：抗-LAM和抗-PIM6 / LAM单克隆抗体用于诊断和治疗结核分枝杆菌感染

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摘要

The present invention broadly provides different compositions, kits, vectors, and methods including monoclonal antibodies directed to epitopes found within lipoarabinomannan (LAM) and phosphatidyl-myo-inositol mannoside 6 (PIM6) for the diagnosis and treatment of Mycobacterium tuberculosis infections.

机译：本发明广泛地提供了不同的组合物，试剂盒，载体和方法，包括针对在脂阿拉伯糖甘露聚糖（LAM）和磷脂酰肌醇甘露糖苷6（PIM6）中发现的表位的单克隆抗体，用于诊断和治疗结核分枝杆菌感染。 展开▼

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公开/公告号US10729771B2

专利类型

公开/公告日2020-08-04

原文格式PDF

申请/专利权人 RUTGERS THE STATE UNIVERSITY OF NEW JERSEY;
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申请/专利号US201716076971

发明设计人 ABRAHAM PINTER;ALOK CHOUDHARY;
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申请日2017-02-01

分类号G01N33/569;A61K39/40;C07K16/12;A61P31/06;A61K39/04;

国家 US

入库时间 2022-08-21 11:27:47

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1. 用于诊断和治疗结核分枝杆菌感染的新颖抗LAM和抗PIM6/LAM单克隆抗体 [P] . 中国专利： CN110092830A . 2019-08-06

2. 用于诊断和治疗结核分枝杆菌感染的新颖抗LAM和抗PIM6/LAM单克隆抗体 [P] . 中国专利： CN109073649A . 2018-12-21

3. NOVEL ANTI-LAM AND ANTI-PIM6/LAM MONOCLONAL ANTIBODIES FOR DIAGNOSIS AND TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTIONS [P] . 美国专利： US2020316199A1 . 2020-10-08

机译：新型抗LAM和ANTI-PIM6 / LAM单克隆抗体用于结核分枝杆菌感染的诊断和治疗

4. NOVEL ANTI-LAM AND ANTI-PIM6/LAM MONOCLONAL ANTIBODIES FOR DIAGNOSIS AND TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTIONS [P] . 美国专利： US2019038747A1 . 2019-02-07

机译：新型抗LAM和ANTI-PIM6 / LAM单克隆抗体用于结核分枝杆菌感染的诊断和治疗

5. NOVEL ANTI-LAM AND ANTI-PIM6/LAM MONOCLONAL ANTIBODIES FOR DIAGNOSIS AND TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTIONS [P] . 欧洲知识产权局专利： EP3414573A4 . 2019-10-30

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