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Biomarker for diagnosis of extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma

机译:诊断肝外胆管癌,肝内胆管癌或胆囊癌的生物标志物

摘要

An object of the present invention is to provide a method for collecting highly accurate data for diagnosis, useful in diagnosing the presence or absence of extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma, and a kit for diagnosis.;When the concentration of CEACAM1 in a blood sample collected from a test subject is detected using a kit for diagnosis comprising an antibody specifically binding to CEACAM1 or a labeled product thereof, or the like and the CEACAM1 concentration is higher than the concentration of CEACAM1 in a blood sample derived from a non-carcinoma control subject or higher than a certain threshold value (cutoff value), data can be collected for diagnosing the test subject as having a high possibility of having extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma.
机译:本发明的目的是提供一种收集用于诊断的高精度数据的方法,该方法可用于诊断肝外胆管癌,肝内胆管癌或胆囊癌的存在与否以及诊断试剂盒。使用包含与CEACAM1或其标记产物特异性结合的抗体等的诊断试剂盒检测从受检者采集的血液样品中CEACAM1的浓度,并且CEACAM1浓度高于血液样品中CEACAM1的浓度。来自非癌对照受试者或高于某个阈值(临界值)的数据,可以收集数据以诊断受试受试者患有肝外胆管癌,肝内胆管癌或胆囊癌的可能性高。

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