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DEVELOPMENT OF BIOMARKER FOR KETOGENIC DIET-BASED CANCER TREATMENT

机译:基于生酮饮食的癌症生物标记物的开发

摘要

A method for selecting a cancer patient for whom a ketogenic diet therapy would be effective and a method for predicting efficacy of a ketogenic diet therapy in a cancer patient are provided. A method is characterized by obtaining a result of analysis of at least one pre-intake candidate substance selected from the group consisting of acylcarnitine(12:0), acylcarnitine(12:1)-2, acylcarnitine(12:1)-3, acylcarnitine(14:1)-1, acylcarnitine(14:2)-1, acylcarnitine(14:2)-2, acylcarnitine(14:3)-2, acylcarnitine(16:1), acylcarnitine(16:2), anandamide, heptadecenoic acid, hypotaurine, linoleylethanolamide, palmitoleic acid, palmitoylcarnitine, phytosphingosine, quinic acid, uric acid, alanine, citrulline, tryptophan and lysine in a serum derived from a cancer patient prior to intake of a ketogenic diet, and using the result of analysis as an indicator.
机译:提供一种选择生酮饮食疗法对其有效的癌症患者的方法,以及一种预测生酮饮食疗法在癌症患者中的功效的方法。一种方法的特征在于获得至少一种选自酰基肉碱(12:0),酰基肉碱(12:1)-2,酰基肉碱(12:1)-3,酰基肉碱(14:1)-1,酰基肉碱(14:2)-1,酰基肉碱(14:2)-2,酰基肉碱(14:3)-2,酰基肉碱(16:1),酰基肉碱(16:2),在摄入生酮饮食之前,从癌症患者获得的血清中,使用大麻素,庚二酸,次牛磺酸,亚牛磺酸,亚油酰乙醇酰胺,棕榈油酸,棕榈酰肉碱,植物鞘氨醇,奎尼酸,尿酸,丙氨酸,瓜氨酸,色氨酸和赖氨酸,并使用生酮饮食分析作为指标。

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